Peter Balint-Kurti

Peter Balint-Kurti, USDA-ARS Research Geneticist at NC State
pjbalint@ncsu.edu
North Carolina State University
Department of Entomology and Plant Pathology
2572 Thomas Hall, CB 7616
Raleigh, NC 27695-7616
(919) 515-3516 (Office) | (919) 515-7376 (Lab) | (919) 856-4816 (Fax)
Lab: 2574 Thomas Hall
Research Interests

We are interested in understanding the genetic and mechanistic bases of disease resistance in maize. Maize is a model genetic system and many resources are available with which we can address this problem.  We hope that findings made will improve the resilience of the maize crop and will  be extrapolated to other plant systems

We work in a number of related areas including:

  •  Analysis of quantitative (partial, polygenic) disease resistance
  • Genetic and biochemical analysis of the maize hypersensitive  defense response.
  • The basal response to microbes  in maize and sorghum
  • Multiple disease resistance in maize.
  • Analysis of the maize microbiome

More details of our research can be found at our home page:

https://sites.google.com/a/ncsu.edu/maize-disease/home

Education
  • Ph.D. Sainsbury Laboratory, John Innes Institute, Norwich, UK, 1994. “Genetic mapping and analysis of two tomato genes for resistance to Cladosporium fulvum.”
  • BA (Plant molecular biology) – Cambridge University, UK, 1990.
Extension & Outreach

We have an active outreach program involving work with local elementary and middle schools and with the NC Museum of Natural Sciences. For more details see my website (https://sites.google.com/a/ncsu.edu/maize-disease/home).  If you would like me to come to talk to your class or group please contact me at the address above.

Selected Publications
Refereed Journals

google scholar
2017

J. Lennon,  Krakowsky, M.,  Goodman, M.,  Flint-Garcia, S., and  Balint-Kurti, P. (2017). Identification of Teosinte (Zea mays ssp. parviglumis) alleles for resistance to southern leaf blight in near isogenic maize lines. Crop Science doi:10.2135/cropsci2016.12.0979

 
X. Zhang, Q. Yang, · Rucker, E., Thomason, W. and Balint-Kurti, P. (2017) Fine mapping of a quantitative resistance gene for gray leaf spot of maize (Zea mays L.) derived from teosinte (Z. mays ssp. parviglumis).   Theoretical and Applied Genetics, 2017. 130(6): p. 1285-1295.
 

Q.Yang, Balint-Kurti, P., Xu, M. (2017) Quantitative Disease Resistance: Dissection and Adoption in Maize. Molecular Plant doi.org/10.1016/j.molp.2017.02.004

X. Zhang, Valdés-López, O., Arellano, C., Stacey, G. and Balint-Kurti, P. (2017). Genetic dissection of the maize (Zea mays L.) MAMP response. Theoretical and Applied Genetics.  130: 1155. doi:10.1007/s00122-017-2876-6

 
2016
 
B. Olukolu, Bian, Y., De Vries, B., Tracy, W.F., Wisser, R., Holland, J. B., and Balint-Kurti, P. J. (2016) The genetics of leaf flecking in maize and its relationship to plant defense and disease resistance.  Plant Physiology DOI:10.1104/pp.15.01870
Minker K, Biedrzycki M, Kolagunda A, Rhein S, Perina F, Jacobs S, Moore, M,, Jamann, T., Yang, Q., Nelson, R., Balint-Kurti, P., Kambhamettu, C., Wisser R., and Caplan J. (2016)  Semiautomated confocal imaging of fungal pathogenesis on plants: Microscopic analysis of macroscopic specimens. Microscopy Research and Technique, DOI: 10.1002/jemt.22709
Olukolu, B., Tracy, W., Wisser, R.,  De Vries, B., and Balint-Kurti, P.  (2016). A genome-wide association study for partial resistance to maize common rust. Phytopathology 106:745-751.


G-F Wang and Balint-Kurti P (2016) Maize Homologs of CCoAOMT and HCT, Two Key Enzymes in Lignin Biosynthesis, Form Complexes with the NLR Rp1 Protein to Modulate the Defense Response. Plant Physiolog
y pp.00224.2016.  http:/​/​dx.​doi.​org/​10.​1104/​pp.​16.​00224


Liu, Z., Cook, J.,Melia-Hancock, S., Guill, K., Bottoms, C., Garcia, A., Ott, O., Nelson, R., Recker, J., Balint-Kurti, P., Larsson, S., Lepak, N., Buckler, E., Trimble, L., Tracy, W., McMullen, M., Flint-Garcia, S. (2016) Expanding maize genetic resources with pre-domestication alleles: maize-teosinte introgression populations.  Plant Genome doi:10.3835/plantgenome2015.07.0053.
 
J. Lennon, M. Krakowsky, M. Goodman, S Flint-Garcia, Peter Balint-Kurti (2016) Identification of alleles conferring resistance to gray leaf spot in maize derived from its wild progenitor species teosinte (Zea mays ssp. parviglumis). Crop Science.56:209-218 doi:10.2135/cropsci2014.07.0468

2015

 
 
G-F Wang, He, Y., Strauch, R., Olukolu, B., Nielsen, D. , Li, X.  and Balint-Kurti, P. (2015) Maize Homologs of Hydroxycinnamoyltransferase , a Key Enzyme in Lignin Biosynthesis, Bind the NLR Rp1 Proteins to Modulate the Defense Response.  Plant Physiology.169: 2230-2243. DOI:10.1104/pp.15.00703

P. Balint-Kurti and J. Holland (2015) New insight into a complex plant–fungal pathogen interaction Nature Genetics 47, 101–103doi:10.1038/ng.3203

V. Vontimitta,  Olukolu, B.,  Penning, B., Johal, G., Balint-Kurti, P. (2015) The genetic basis of flecking and its relationship to disease resistance in the IBM maize mapping population. Theoretical and Applied Genetics. 128:2331-9 .DOI: 10.1007/s00122-015-2588-8.

G-F Wang and Balint-Kurti P. (2015)  Cytoplasmic and nuclear localizations are important for the hypersensitive response conferred by maize autoactive Rp1-D21 protein. Molecular Plant-Microbe Interactions. 28,  1023-1031

 
G-F Wang, Ji J,  EI-Kasmi, F,  Dangl, J, Johal G, Balint-Kurti P. (2015) Molecular and Functional Analyses of a Maize Autoactive NB-LRR Protein Identify Precise Structural Requirements for Activity.  PLOS Pathogens, DOI: 10.1371/journal.ppat.1004674
R. C. Pratt, J. B. Holland, P. J. Balint-Kurti, N. D. Coles, J. Zwonitzer, M. A. Casey, and M. D. McMullen (2015) Registration of the Ki14 × B73 Recombinant Inbred Mapping Population of Maize. Journal of Plant Registrations. doi:10.3198/jpr2014.06.0041crmp.
 

2014

Y. Bian, Q. Yang, P. Balint-Kurti, R. Wisser, J. Holland (2014) Limits on the reproducibility of marker associations with southern leaf blight resistance in the maize nested association mapping populationBMC Genomics 2014, 15:1068

B Olukolu, Wang G-F, Vontimitta V, Venkata BP , Marla S, Ji J, Gachomo E, Chu K, Negeri A, Benson J, Nelson R , Bradbury P, Nielsen D, Holland J B, Balint-Kurti PJ and Johal G. (2014)  A Genome-Wide Association Study of the Maize Hypersensitive Defense Response Identifies Genes That Cluster in Related Pathways. PLoS Genetics DOI: 10.1371/journal.pgen.1004562

Manching, H. Balint-Kurti, P. and Stapleton, A. (2014) Nitrogen stress reduces fungal pathogen symptoms and dampens the correlation between disease and early-season bacterial epiphyte diversity in maize. Frontiers in Plant Science doi: 10.3389/fpls.2014.00403

Santa-Cruz, J. H., Kump, K. L., Arellano, C. , Goodman, M., Krakowsky, M. D., Holland, J. B. , Balint-Kurti, P. J. (2014) Evaluation of two southern leaf blight resistance QTL for their effect on yield and disease resistance in isogenic maize hybrids. Crop Science 54: 882-894

 

2013

Benavente, L., Ding, X., Redinbaugh, M., Nelson, R., and Balint-Kurti, P. (2013) Virus-Induced Gene Silencing in Diverse Maize Lines Using the Brome Mosaic Virus-based silencing vector. Maydica 57(3/4):206-214

Negeri, A., Wang, G-F., Benavente, L., Kibiti, C., Chaikam, V., Johal, G., Balint-Kurti, P. (2013) Characterization of temperature and light effects on the defense response phenotypes associated with the maize RP1-D21 gene. BMC Plant Biology 13:106

Olukolu, B., Negeri, A., Dhawan, R. , Venkata, B. P. , Sharma, P., Garg, A. , Gachomo, E. , Marla, S., Chu, K., Hasan, A. , Ji, J. , Chintamanani, S., Green, J. , Holland, J., Wisser, R. , Shyu, C.-R., Johal, G., Balint-Kurti, P. (2013) A genome-wide association analysis identifies loci that modulate hypersensitive response caused by a maize auto-active resistance gene. Genetics 193:609-620

2012

Green, J.M, Appel, H., Rehrig, E. M., Harnsomburana, J., Chang, J-F., Balint-Kurti, P., Shyu, C-R., (2012) PhenoPhyte: A flexible affordable method to quantify visual 2D phenotypes. Plant Methods. 8:45. doi:10.1186/1746-4811-8-45

Veturi, Y., Kump, K., Walsh, E., Oliver, O., Poland , J., Kolkman, J., Balint-Kurti, P., Holland, J., Wisser , R., (2012) Multivariate mixed linear model analysis of longitudinal data: an information-rich statistical technique for analyzing disease resistance data. Phytopathology 102, 1016-1025

Belcher, A., Zwonitzer, J., Santa Cruz, J., Krakowsky, M., Chung, C-L. Nelson, R., Arellano, C., Balint-Kurti, P. (2012) Analysis of Quantitative Disease Resistance to Southern Leaf Blight and of Multiple Disease Resistance in Maize Using Near-Isogenic Lines. 124:433-445. Theoretical and Applied Genetics.

 

2011

Balint-Kurti, P., Pridgen, P. and Stapleton, A.. (2011). Application of an antibiotic resets the maize leaf phyllosphere community and increases resistance to southern leaf blight. Acta Hort. (Ishs) 905:57-62. http://www.actahort.org/books/905/905_4.htm

Chaikam, V. Negeri, A, Dhawan, D., Puchaka, B. , Ji, J., Chintamanani,, S., Gachomo, E., Zillmer, A., Doran, T., Weil, C., Balint-Kurti, P., Johal, G. (2011) Use of Mutant-Assisted Gene Identification and Characterization (MAGIC) to identify novel genetic loci that modify the maize hypersensitive response . Theoretical and Applied Genetics 123(6):985-97.

Negeri, A ., Coles, N., Holland, J., Balint-Kurti, P.. Mapping QTL controlling southern leaf blight resistance by joint analysis of three related recombinant inbred line populations (2011) Crop Science 51:1571-1579

Wisser, R., Kolkman, J., Patzoldt, M., Holland, J., Yu, J., Krakowsky, M., Nelson, R., and Balint-Kurti, P. (2011) : Multivariate analysis of maize disease resistances suggests a pleiotropic genetic basis and implicates a GST gene.  Proceedings of the National Academy of Sciences 108:7339-7344

Kump, K., Bradbury, P., Buckler, E., Belcher, A., Oropeza-Rosas, M., Wisser, R., Zwonitzer, J., Kresovich, S., McMullen, M., Ware, D., Balint-Kurti, P., and Holland, J. (2011) Genome-wide association study of quantitative resistance to southern leaf blight in the maize nested association mapping population. Nature Genetics 43:163-168

Kump, K., Holland, J., Jung, M., Wolters, P., Balint-Kurti, P. (2010) Joint analysis of near isogenic and recombinant inbred line populations yields precise positional estimates for QTL. Plant Genome 3:142–153

Wisser, R., Balint-Kurti, P, Holland, J. (2011) A novel genetic framework for studying response to artificial selection. Plant Genetic Resources. Published Online DOI:10.1017/S1479262111000359

Chung,C-L., Poland, J., Kump, K., Benson, J., Longfellow, J., Walsh, E., Balint-Kurti, P. and Nelson, R. (2011)Targeted discovery of quantitative trait loci for resistance to northern leaf blight and other diseases of maize. Theoretical and Applied Genetics 123:307-326

 

2010

Zhang, J., Martin, J., Balint-Kurti, P., Huang, L., Giroux, M. (2010). The wheat puroindoline genes confer fungal resistance in transgenic corn. Journal of Phytopathology 159:188-190

Chung C-L, Longfellow, J., Walsh, E., Kerdieh, Z., Van Esbroeck, G., Balint-Kurti, P., Nelson, R. (2010). Resistance loci affecting distinct stages of fungal pathogenesis: use of introgression lines for QTL mapping and characterization in the maize – Setosphaeria turcica pathosystem . BMC Plant Biology 10:103.

Chintamanani, S, Hulbert,S.H.,, Johal, G.S., Balint-Kurti, P. (2010) Identification of a Maize Locus that Modulates the Hypersensitive Defense Response, Using Mutant-Assisted Gene Identification and Characterization (MAGIC). , Genetics 184: 813–825

Balint-Kurti, P., Yang, J., Esbroek, G.V. Jung, J. and Smith, E. (2010) Use of a maize Advanced Intercross Line population for Mapping of Quantitative Trait Loci for northern leaf blight resistance and for the investigation of multiple disease resistance. Crop Science 50: 458-466.

Zwonitzer, J., Coles, N., Krakowsky, M., Holland, J., McMullen, M., Pratt, R. and Balint-Kurti, P. (2010) Mapping disease resistance QTL for three foliar diseases of maize in a recombinant inbred line population. -Evidence for Multiple Disease Resistance? Phytopathology 100:72-79.

Coles, N., McMullen, M. , Balint-Kurti, P., Pratt, R.,, and Holland, J. (2010) Genetic Control of Photoperiod Sensitivity in Maize Revealed by Joint Multiple Population Analysis Genetics 184: 799–812

Balint-Kurti, P., Simmons, S., Blum J., Ballaré C. and A. Stapleton.. (2010). Maize Leaf Epiphytic Bacteria Diversity Patterns Are Genetically Correlated with Resistance to Fungal Pathogen Infection. Molecular Plant-Microbe Interactions. 23: 473-484

 

2008

Williams, W., Krakowsky, M., Windham, G., Balint-Kurti, P., Hawkins, L., Henry, W.. (2008). Identifying Maize Germplasm with Resistance To Aflatoxin Accumulation. Journal of Toxicology-Toxin Reviews 27:319-345.

Poland, J. , Balint-Kurti, P. , Wisser, R., Pratt, R., Nelson, R. (2008). Shades of gray: The world of quantitative disease resistance. Trends in Plant Science, 14:21-29

Zwonitzer, J., Bubeck, D., Bhattramakki, D., Goodman, M., Arellano, C., Balint-Kurti, P.( 2008). Use of backcross recurrent selection and QTL mapping to identify loci contributing to SLB resistance in a highly resistant maize line. Theor. Appl. Genet. 118:911-25

Johal, G., Balint-Kurti, P., and Weil C. (2008). Mining and harnessing natural variation – current approaches and a little MAGIC. Crop Science 48: 2066-2073.

Balint-Kurti, P., R.J. Wisser, and J. Zwonitzer.( 2008). Use of the an Advanced Intercross Population for Precise Mapping of Quantitative Trait Loci for Gray Leaf Spot Resistance in Maize. Crop Science 48:1696-1704.

Balint-Kurti, P.J., J.C. Zwonitzer, M.E. Pe, G. Pea, M. Lee, and A.J. Cardinal. (2008). Identification of Quantitative Trait Loci for Resistance to Southern Leaf Blight and Days to Anthesis in Two Maize Recombinant Inbred Line Populations. Phytopathology 98:315-320.

2007

Gao, X., Shim, W-B., Göbel, C., Kunze, S., Feussner, I., Meeley, R., Balint-Kurti P., and Michael Kolomiets (2007) Disruption of a maize 9-lipoxygenase results in increased resistance to fungal pathogens and reduced levels of contamination with mycotoxin fumonisin. Mol. Plant-Microbe Int. 20:922-933.

Balint-Kurti, P.J., Zwonitzer, J.C. Wisser, R.J., Carson, M.L., Oropeza-Rosas, M., Holland, J.B., and Szalma, S.J. (2007) Precise mapping of quantitative trait loci for resistance to southern leaf blight, caused by Cochliobolus heterostrophus race O, and flowering time using advanced intercross maize lines. Genetics 176:645-657.


2006

Jines, M., Balint-Kurti, P., Robertson-Hoyt, L., Molnar, T., Holland, J., and Goodman, M. (2006) Mapping Resistance to Southern Rust In a Tropical By Temperate Maize Recombinant Inbred Topcross Population. TAG 114:659-667.

Balint-Kurti, P.J., Krakowsky, M. D., Jines, M. P., Robertson, L. A., Molnár, T. L., Goodman M. M. and Holland J. B. (2006) Identification of Quantitative Trait Loci for Resistance to Southern Leaf Blight and Days to Anthesis in a Maize Recombinant Inbred Line Population. Phytopathology 96:1067-1071

Robertson, L., Jines, M., Balint-Kurti, P., Kleinschmidt, C., White, D., Payne, G., Maragos, C. and Holland, J.(2006) Mapping of QTL for Ear Rot and Fumonisin Accumulation in Maize. Crop Science 46:1734-1743.

Wisser, R. J., Balint-Kurti, P. J. and Nelson R. J. (2006) The genetic architecture of disease resistance in maize: a synthesis of published studies. Phytopathology 96:120-129.

Carson, M. L., Balint-Kurti, P. J., Blanco, M., Millard, M., Duvick, S., Holley, R., Hudyncia, J., and Goodman, M. M. (2006) Registration of 9 high-yielding tropical by temperate maize germplasm lines adapted for the southern US. . Crop Science 46:1825-1826.

2005

Balint-Kurti, P. J., Blanco, M., Millard M., Duvick, S., Holland, J., Clements, M., Holley, R., Carson, M and Goodman, M. M. Registration of 20 GEM breeding families adapted for the southern US (2005). Crop Science 46:996-998

Balint-Kurti, P. J. and Carson, M. L. (2005) Analysis of quantitative trait loci for resistance to southern leaf blight in juvenile maize. Phytopathology 96:221-225.

Pre-2005

Brummell, D. A., Balint-Kurti, P. J., Harpster, M. H., Palys, J. M., Oeller, P.W. and Gutterson, N. (2003) Inverted repeat of a heterologous 3′-terminator for high efficiency, high-throughput gene silencing. Plant Journal 33: 793-800.

Balint-Kurti, P. J., Churchill, A.C.L. and May G.D. (2001). Development of a transformation system for Mycosphaerella pathogens of Banana: A tool for the study of host/pathogen interactions. FEMS Microbiol. Letters 195: 9-15.

Ganapathi T. R., Higgs N. S., Balint-Kurti P. J., Arntzen C. J., May G. D and Van Eck J. M. (2001) Agrobacterium-mediated transformation of embryogenic cell suspensions of the banana cultivar Rasthali (AAB). Plant Cell Reports 20:157-162.

Peumans, W., Zhang, W., Barre, A., Astoul, C., Balint-Kurti, P., Rovira, P., Rougè, P., May, G., Van Leuven, F., Truffa-Bachi, P. and Van Damme, E. (2000). Fruit-specific lectins from banana and plantain. Planta 211:546-554.

Balint-Kurti P. J., Clendennen S. K., Dolezelová M., Valárik M., Dolezel J., Beetham P. R. and. May G. D (2000) Identification and chromosomal localization of the monkey retrotransposon in Musa sp. Molec. and Gen. Genet. 263:908-915.

Balint-Kurti, P.J., Ginsburg, G., Liu, J. and Kimmel, A.R. (1998). Non-autonomous regulation of a graded, PKA-mediated transcriptional activation signal for cell patterning. Development 125:3947-3954.

Balint-Kurti, P.J., Ginsburg, G., Rivero-Lezcano, O. and Kimmel, A.R. (1997). rZIP, a RING-leucine zipper protein that regulates cell fate determination during Dictyostelium development. Development 124:1203-1213.

Thomas, C., Jones, D., Parniske, M., Harrison, K., Balint-Kurti, P., Hatzixanthis, K. and Jones, J. (1997). Characterization of the tomato Cf-4 gene for resistance to C. fulvum identifies sequences that determine recognitional specificity in Cf-4 and Cf-9. Plant Cell 9:2209-2224.

Balint-Kurti, P.J., Jones, D.A. and Jones, J.D.G., (1995). Integration of the classical and molecular maps of the short arm of tomato chromosome 1. TAG 90:17-26.

Jones, D.A., Thomas, C.M., Hammond-Kosack, K.E., Balint-Kurti, P.J. and Jones J.D.G. (1994). Isolation of the tomato Cf-9 gene for resistance to Cladosporium fulvum by transposon tagging. Science 266:789-793.

Balint-Kurti , P.J., Dixon, M.S., Jones, D.A.., Norcott, K.A.. and Jones, J.D.G. (1994). RFLP linkage analysis of the tomato Cf-4 and Cf-9 genes for resistance to Cladosporium fulvum. TAG 88:691-700.

Jones, D.A,. Dickinson, M.J., Balint-Kurti, P.J., Dixon, M.S. and Jones J.D.G. (1993). Two complex resistance loci revealed in tomato by classical and RFLP mapping of the Cf-2, Cf-4, Cf-5 and Cf-9 genes for resistance to C. fulvum. Molec. Plant-Microbe Int. 6: 348-357.

Book Chapters etc.

Jamann, T., Balint-Kurti, P. and Holland, J. (2014) QTL Mapping Using High-Throughput Sequencing. In press. Chapter in “Plant Functional Genomics:” Ed J. Alonso,

Balint-Kurti, P., Shew, D. and Cowger, C. (2014) Host Resistance. In Press. Chapter in “Plant Pathology: Concepts and Laboratory Excercises” Ed.s Ownley, B,. and Trigiano, R.

Jamann, T., Nelson, R. and Balint-Kurti, P. (2013). Maize Disease Resistance. Chapter 3“Translational Genomics for Crop Breeding, Volume I: Biotic Stresses” Eds. Roberto Tuberosa and Rajeev Varshney (Wiley-Blackwell)

Balint-Kurti, P.J., and G.S. Johal. (2011). Use of Mutant-assisted Gene Identification and Characterization (MAGIC) to Identify Useful Alleles for Crop Improvement ISB News Reports January 2011:pp.1-3.

Balint-Kurti, P.J. and Johal, G.S. (2008). Maize Disease Resistance. Chapter in “The Maize Handbook”, eds. Sarah Hake, Jeff Bennetzen. Chapter in “Handbook of Maize: Its Biology” eds. Sarah Hake, Jeff Bennetzen. (Springer).pp229-250

Balint-Kurti, P. and Churchill, A. (2004) Towards a molecular understanding of Mycosphaerella/banana interactions. In Banana Improvement: Cell. and Molec. Biology, and Induced Mutations. pp.147-160. S.M. Jain (Editor) Kluwer.

Mercier, J., Howie W.J., and Balint-Kurti P. (2001). A detached leaf assay to evaluate the resistance of banana to Mycosphaerella fijiensis. Phytopathology 91:S61. (Abstract)

Balint-Kurti, Firoozabady, Moy, Y., Mercier, R., Fong,., Wong, and Gutterson. (2001) Better bananas – the biotech way. Infomusa 10:vi..

Rogers, K.C., Ginsburg, G.T., Mu, X., Gollop, R., Balint-Kurti, P.J., Louis, J.M. and Kimmel, A.R. (1997), The cAMP gene family of D. discoideum: expression, regulation, function. Dictyostelium-A Model System for Cell and Devel. Biol. (Universal Acad. Press, Inc.) 163-172.

Balint-Kurti, P.J. (1994). The cloned tomato peroxidase genes pTAP1 and pTAP2 correspond to the linked isozymes Prx2 and Prx3. Tomato Genetics Co-op. Report 44:5.

Balint-Kurti, P., Jones, D. and Jones, J. (1994). Dominance of Lapageria (Lpg) is reversed in crosses with Lycopersicon pennellii. Tomato genetics Co-op. Report 44:5.

Jones, D.A., Balint-Kurti, P.J., Dickinson, M.J., Dixon, M.S. and Jones, J.D.G. (1992). Locations of genes for resistance to C. fulvum on the classical and RFLP maps of tomato. Tomato Genetics Co-op Report 42